Eh, it's pretty deserved. He's got a whole complex about making himself as miserable as possible, this just facilitates that and adds the extra layer of involuntary celibacy.

[No sympathy for Angel. He's hot, though, in Spike's opinion, if that matters. Spike wants to kill him one day.]

It's the only case I know of, but from what I understand, it's probably possible in other ways. Look at this guy right here, for one. [Nudges his Daemon.] That's a portion of my severed soul.